The consensus from what I've read is as follows:
Wipe the ball with a microfiber towel after every shot.
Clean the ball after every bowling session with either a bowling specific cleaner or some other cleaner, like a mixture of Simple Green and alcohol. Ideally this is done before leaving the bowling center.
After 60 to 100 games the ball should have a deep cleaning.
For more detail see the following thread: http://www.bowlingboards.com/threads...nd-Maintenance
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