If I'm understanding you correctly and if the blister is where you say it is then the span of your holes might be incorrect. With your fingertips in the ball, you shouldn't have that much pressure at that point on your hand. Also, if it is drilled correctly, you shouldn't have so much pressure at that point on your thumb. Your hand should be nearly relaxed without dropping the ball. And when you release the ball, it should just come out of the ball with no effort/pressure. It sounds to me like you're having to "grab" the ball.
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