If I understand the USBC rules on pre-bowling, you must pre-bowl with a legal line-up. So for the most part, if a team has no one to sub and one or more bowlers will be missing, the whole team pre-bowls with the opposing team having the option of pre-bowling against them. Youth leagues expressly allow individual pre-bowling. For adults it’s expressly forbidden since one bowler is almost never a legal line-up.
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